Rebel forces opposing President Bashar al-Assad have launched their biggest offensive in years this week, controlling a majority of Syria's second city of Aleppo according to a monitor.
Government forces offered little resistance, the war monitor said, and the army admitted that rebels had entered "large parts" of the city.
Syrian rebels are now advancing towards the city of Hama, claiming to already control six towns on this axis, according to local sources.
The jihadists also claimed to have cut off the international Aleppo-Raqqa road from the Kweiris airport in rural Aleppo, according to the same sources.
Why have the Syrian rebels and their allies from Turkish-backed factions decided to attack after years of relative calm, and what is at stake?
Why now?
On Wednesday, Hayat Tahrir al-Sham (HTS), a jihadist alliance led by Al-Qaeda's former Syria branch, and allied factions attacked government-held areas of the northern province of Aleppo and the northwestern Idlib region.
The Britain-based Syrian Observatory for Human Rights war monitor said the rebels had seized dozens of towns and villages in the north and "took control of most of" Aleppo.
The violence has killed at least 311 people, mostly combatants on both sides, but also including at least 28 civilians, said the Observatory, which relies on a network of sources inside Syria.
The rebels, working in a joint operations room, launched their attack the same day a Hezbollah-Israel truce came into effect in neighbouring Lebanon.
During more than 13 months of hostilities, Israel also intensified attacks on Iran-backed groups in Syria including Hezbollah, which for years has fought on the side of Damascus in the country's civil conflict.
Along with Iran, Russia is also a close ally of Syrian President Bashar al-Assad, with Moscow intervening in Syria's civil war in 2015, turning the momentum of the conflict in favour of Damascus.
Turkey has positioned itself as a possible mediator in the Ukraine war and is a key trade and finance centre for Western-sanctioned Moscow.
What major powers are at play ?
The main powers backing each side of the conflict have so far refrained from making escalatory remarks.
The Kremlin on Friday said it hoped Syria would quickly "restore order" in Aleppo, while Tehran has blamed the offensive on an American-Israeli plot to destabilise the region.
Turkey has demanded an end to "attacks" on the rebel enclave of Idlib in Syria, where Syrian and Russian warplanes launched air strikes.
The mass offensive comes as a potential rapprochement between Damascus and Ankara has stalled in recent years, though Moscow and Tehran have pushed for a detente.
Turkish forces and Turkey-backed rebel factions control swathes of northern Syria.
Ankara initially sought to topple Assad after the Syrian conflict erupted in 2011, but as government forces regained territory, Turkish President Recep Tayyip Erdogan reversed course.
In a post on X, Caroline Rose, of the Washington-based New Lines Institute, said the Aleppo offensive appears to be "a way to force the regime to negotiate with a weakened hand".
What about the government ?
The Syrian government has reeled from its biggest loss of territory in years this week.
The rebels also cut off the Damascus-Aleppo M5 highway, in addition to controlling the strategic M5-M4 junction that also connects Syria's second city to regime stronghold Latakia, on the Mediterranean coast.
Rami Abdel Rahman, who heads the Syrian Observatory for Human Rights, said the rebels advanced into Aleppo "without any significant pushback from regime forces".
"It is strange to see regime forces being dealt such big blows despite Russian air cover and early signs that HTS was going to launch this operation," Abdel Rahman said.
Damascus has largely relied on Russian air power and Hezbollah fighters on the ground to regain swathes of Syria lost to rebels early in the war.
But the Iran-backed Hezbollah has taken heavy losses in its war with Israel.
Meanwhile, "Russia's presence has thinned out considerably and quick reaction air strikes have limited utility", said Aaron Stein, president of the US-based Foreign Policy Research Institute.
Speedy rebel advances are "a reminder of how weak the regime is and, perhaps, how they have grown complacent in the last couple of years" as battles wound down, he said.
Aya Iskandarani, with AFP
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